TECHNOLOGY

Heliored: Heal | Renew

RED LIGHT PHOTOBIOMODULATION

Absorption by Cytochrome c Oxidase (CCO)

Mitochondria contain a key enzyme in the electron transport chain called cytochrome c oxidase (CCO). CCO absorbs light in the red (600-700nm) allowing more efficient electron transfer.

This enhances ATP (adenosine triphosphate) production, the energy currency of cells.

Nitric Oxide (NO) Release & Oxygen Utilization

Under stress, nitric oxide (NO) binds to CCO, which blocks oxygen from being used efficiently in the mitochondria.Red light at 625nm displaces NO from CCO, freeing it to restore proper mitochondrial function and ATP production.

Reduced Oxidative Stress & Inflammation

Increased ATP production improves cellular function, reducing oxidative stress by balancing reactive oxygen species (ROS).

This leads to lower inflammation and enhanced cell repair mechanisms.

Enhanced Blood Flow & Tissue Repair

The release of NO also causes vasodilation, improving oxygen and nutrient delivery to tissues. This effect is beneficial for wound healing, muscle recovery, and reducing pain.

But how does all this help your mouth?

Well...

Enhancing Mitochondrial Function in Oral Tissues

Oral tissues, like gum cells and bone, contain mitochondria-rich cells that respond well to red light.

Red light at 625nm enhances ATP production, accelerating gum healing, bone regeneration, and reducing oral inflammation.

Pain Relief for TMJD & Oral Surgery Recovery

Temporomandibular Joint (TMJ) disorders often involve muscle inflammation and nerve pain.

RLT helps reduce pain and stiffness by improving blood circulation, relaxing muscles, and lowering oxidative stress in the jaw area.

Post-extraction healing (after wisdom teeth removal) is faster with RLT, as it reduces swelling and enhances tissue regeneration.

Gum Health & Periodontal Disease

Gingivitis & Periodontitis: Red light therapy helps reduce inflammation, bacterial load, and oxidative stress in gum tissues.

Studies suggest RLT can enhance fibroblast activity, leading to better collagen production and faster gum tissue repair.

Tooth Sensitivity & Nerve Healing

Dentinal hypersensitivity (tooth sensitivity) is often linked to inflamed nerve endings.

RLT can stimulate nerve repair, reduce inflammation, and promote enamel remineralisation when combined with appropriate dental treatments.

Root Canal Therapy & Infection Control

Studies suggest red light (along with antimicrobial blue light or near-infrared light) can help reduce oral bacterial biofilms, making it a potential adjunct to root canal disinfection.

Photobiomodulation (PBM) can also help reduce post-root canal pain and inflammation.

What about blue?

470nm blue light has several benefits for oral health due to its antimicrobial and healing properties:

Antibacterial Effects

Blue light at 470nm is effective against harmful oral bacteria, particularly those responsible for plaque, cavities, and gum disease (Porphyromonas gingivalis and Streptococcus mutans).

It works by producing reactive oxygen species (ROS) within bacteria, leading to their destruction without harming surrounding tissues.

Teeth Whitening

470nm blue light is commonly used in whitening treatments. It activates the PAP in the Helioblue whitening pen, speeding up the oxidation process to remove stains.

Supports Wound Healing

It can enhance tissue repair and accelerate healing after dental procedures like extractions, implants, or ulcers by modulating bacteria and reducing excessive inflammation by inhibiting the release of pro-inflammatory cytokines

May Reduce Bad Breath

By eliminating odor-causing bacteria, blue light therapy can help freshen breath.

Scientific Support & Dental Applications

Numerous studies have explored low-level laser therapy (LLLT) in dentistry, with strong evidence supporting its role in reducing pain, enhancing healing, and improving overall oral health.

NASA's research on light therapy for wound healing has also been extended to oral tissues and gum regeneration.